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Study Outline
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Chapter 4: Cellular Form and Function
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Concepts of Cellular Structure (pp.107-111)
- Development of the cell theory
a. Early studies of Hooke and Schwann
b. The spontaneous generation issue
c. Tenets of the cell theory
- Cell shapes
a. Terms for cell shapes
b. Surfaces of epithelial cells
- Cell size
a. Sizes of human cells
b. Limitations on size
- An evolving perspective on cells
a. Microscopes and resolution
b. Internal organization of a cell
The Cell Surface (pp. 111-117)
- The plasma membrane
a. Membrane lipids
- Phospholipid bilayer
- Cholesterol
- Glycolipids
b. Membrane proteins
- Integral proteins
- Peripheral proteins
c. Functions of membrane proteins
- Receptors for chemical messengers
- Second messenger systems
- Messenger deactivators
- Channels and gates
- Carriers and pumps
- Motor molecules
- Cell identity markers
- The glycocalyx
a. Composition
b. Functions
- Extensions of the cell surface
a. Microvilli (brush border)
- Core of microfilaments
- Absorptive and sensory roles
b. Cilia
- Power and recovery strokes
- Importance of saline layer
- 9+2 structure of axoneme
- Basal body
- Sensory roles
c. Flagella
The Cell Interior (pp. 117-123)
- Organelles
a. The nucleus
b. Rough endoplasmic reticulum
c. Ribosomes
d. Golgi complex and vesicles
e. Lysosomes
f. Peroxisomes
g. Mitochondria
h. Smooth endoplasmic reticulum
i. Centrioles
- Cytoskeleton
a. Microfilaments
b. Intermediate filaments
c. Microtubules
- Inclusions
Membrane Transport-Passive Mechanisms (pp.123-128)
- Selective permeability
- Filtration
- Simple diffusion
a. Concentration gradients
b. Factors affecting diffusion rate
- Osmosis
a. Osmotic pressure
- Tonicity
- Facilitated diffusion
- Carrier-mediated transport
a. Specificity
b. Saturation
Membrane Transport-Active Mechanisms (pp.128-135)
- Active transport
a. Movement up a gradient
b. Use of ATP
c. Steps in active transport
- Symport and antiport systems
a. The Na+-K+ pump as an antiport system
- Mechanism
- Functions
- Regulation of cell volume
- Maintenance of membrane potential
- Bulk transport
a. Endocytosis
- Phagocytosis
- Pinocytosis
- Receptor-mediated pinocytosis
b. Exocytosis


