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Study Outline
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Chapter 6: Histology
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The Study of Tissues (pp.170-172)
- Interpretation of tissue sections
- The primary germ layers
- The primary tissue classes (table 6.1)
- Composition of tissues
a. Cells
b. Matrix (extracellular material)
Excitable Tissues (pp.172-175)
- Muscular tissue (table 6.2)
a. General properties and functions
b. Skeletal muscle
c. Cardiac muscle
d. Smooth muscle
- Nervous tissue
a. Neurons
b. Neuroglia
Embryonic and Fibrous Connective Tissues (pp.175-182)
- Overview of connective tissue (table 6.3)
a. General characteristics
- Most variable tissue type
- Usually more matrix than cell volume
- Often supports other tissues or binds organs
b. Functions
- Embryonic connective tissue
a. Mesenchyme
b. Mucous connective tissue
- Components of fibroconnective tissue
a. Cells
- Fibroblasts
- Histiocytes (tissue macrophages)
- Leukocytes (white blood cells)
- Plasma cells
- Mast cells
- Adipocytes (fat cells)
b. Fibers
- Collagenous (white) fibers
- Reticular fibers
- Elastic (yellow) fibers
c. Ground substance
- Tissue (interstitial) fluid
- Minerals (mainly calcium salts)
- Proteoglycans
- Protein (minor component)
- Glycosaminoglycans (GAGs)
- Types of fibroconnective tissue
a. Loose connective tissue
- Areolar tissue
- Adipose tissue: white and brown fat
- Reticular tissue
b. Dense connective tissues
- Dense regular connective tissue
- Yellow elastic tissue
- Dense irregular connective tissue
Supportive and Fluid Connective Tissues (pp.182-185)
- Cartilage
a. Stiff matrix due to chondroitin sulfate
b. Chondrocytes and lacunae
c. Hyaline cartilage
d. Elastic cartilage
e. Fibrocartilage
- Bone (osseous tissue)
a. Types: Spongy and compact
- Osteocytes in lacunae
- Lamellae surrounding haversian canal
- Dental tissues
- Blood and lymph
a. Plasma (matrix)
b. Formed elements
- Erythrocytes
- Leukocytes
- Platelets
c. Lymph
Epithelial Tissue (pp.185-191)
- Definition and general properties
a. Layers of cells covering or lining surfaces
b. Scanty extracellular material
c. No blood vessels
d. Supported on basement membrane
e. Classification (table 6.4)
- Simple epithelia
a. Simple squamous
b. Simple cuboidal
c. Simple columnar
d. Pseudostratified
- Stratified epithelia
a. Stratified squamous
b. Stratified cuboidal
c. Stratified columnar
d. Transitional
Intercellular Junctions, Glands, and Membranes (pp.191-196)
- Intercellular junctions
a. Tight junctions
b. Desmosomes and hemidesmosomes
c. Gap (communicating) junctions
- Glands
a. Endocrine glands
- Ductless
- Secrete hormones into blood
b. Exocrine glands
- Usually have ducts
- Produce secretions other than hormones
- Some unicellular
c. Exocrine gland structure
- Stroma (connective tissue)
- Parenchyma (secretory portion)
- Divided into lobes and lobules
- Ducts
- Simple glands: unbranched ducts
- Compound glands: branched ducts
d. Classification by type of secretion
- Serous glands
- Mucous glands
- Mixed glands
- Cytogenic glands
e. Classification by method of secretion
- Merocrine glands
- Holocrine glands
- Apocrine glands (modified merocrine glands)
- Membranes
a. Cutaneous membrane
b. Mucous membranes (mucosae)
- Epithelium
- Lamina propria
- Muscularis mucosae
c. Serous membranes (serosae)
- Mesothelium
- Areolar tissue
d. Endothelium of circulatory system
e. Synovial membranes of joints
Tissue Transformations (pp.196-197)
- Differentiation
- Anaplasia (dedifferentiation)
- Hyperplasia (cell multiplication)
- Hypertrophy (cell growth)
- Neoplasia (tumor development)
- Metaplasia (change in tissue type)
- Atrophy
- Necrosis (tissue death)
- Repair


