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Study Outline
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Chapter 14: The Central Nervous System
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Characteristics of the Central Nervous System (pp.463-467)
- Major landmarks
a. Cerebrum
- Cerebral hemispheres
- Gyri, sulci, and fissures
- Corpus callosum
b. Cerebellum
c. Brainstem
d. Gray and white matter
e. Ventricles and central canal
- Embryonic development
a. Neural plate, groove, and folds
b. Neural tube
c. Neural crest
d. Prosencephalon (forebrain)
- Telencephalon
- Diencephalon
e. Mesencephalon (midbrain)
f. Rhombencephalon (hindbrain)
- Metencephalon
- Myelencephalon
Meninges, Cerebrospinal Fluid, Ventricles, and Blood Supply (pp.467-471)
- Meninges
a. Dura mater
- Periosteal layer
- Meningeal layer
- Dural sinuses
b. Meningeal specializations
- Falx cerebri
- Tentorium cerebelli
- Diaphragma sellae
c. Variations in spinal meninges
- Dural sheath
- Epidural space
d. Arachnoid membrane
e. Pia mater
- Cerebrospinal fluid
a. Functions
b. Choroid plexuses
c. Blood-CSF barrier
- Ventricles and CSF circulation
- Blood supply and the blood-brain barrier
a. Rate of flow
b. Blood-brain barrier (BBB)
c. Circumventricular organs
The Spinal Cord (pp.471-477)
- Functions
a. Conduction
b. Locomotion
c. Reflex control
- Gross anatomy
a. Diameter and length
b. Four regions
c. Segmental arrangement
d. Cervical and lumbar enlargements
e. Conus medullaris and filum terminale
f. Cauda equina
- Cross-sectional anatomy
a. Relationship to vertebrae and meninges
b. Anterior median fissure and posterior median sulcus
c. Gray matter
- Dorsal and ventral horns
- Gray commissure and central canal
- Lateral horns in thoracic region
d. White matter
- Columns (funiculi)
- Tracts (fasciculi)
- Decussation of nerve fibers
- Spinal tracts
a. Ascending tracts
- Fasciculus gracilus
- Fasciculus cuneatus
- Dorsal and ventral spinocerebellar
- Spinothalamic
b. Descending tracts
- Tectospinal
- Corticospinal (pyramidal)
- Lateral and medial reticulospinal
- Vestibulospinal
The Hindbrain and Midbrain (pp.477-482)
- Myelencephalon (medulla oblongata)
a. Anatomy
- Pyramids
- Olive and inferior olivary nucleus
b. Functions
- Conduction pathways (tracts)
- Origin of cranial nerves IXXII
- Cardiac center
- Vasomotor center
- Respiratory centers
- Other visceral control centers
- Metencephalon
a. Pons
- Conduction pathways (tracts)
- Nuclei and functions
- Origin of cranial nerves VVIII
b. Cerebellum
- Location
- Hemispheres and vermis
- Gyri (folia), sulci, and fissures
- Cerebellar peduncles
- Arbor vitae
- Purkinje cells
- Role in motor coordination
- Mesencephalon (midbrain)
a. Cerebral aqueduct
b. Origin of cranial nerves IIIIV
c. Cerebral peduncles
d. Substantia nigra
e. Tegmentum and red nucleus
f. Tectum and corpora quadrigemina
- Superior colliculi
- Inferior colliculi
- Reticular formation
a. Location and structure
b. Functions
The Diencephalon (pp.482-484)
- Thalamus
a. Location and anatomy
b. Functions
- Hypothalamus
a. Location and anatomy
b. Functions
- Food and water intake
- Thermoregulation
- Cardiovascular regulation
- Hormone secretion
- Sleep and waking
- Emotional behavior
- Epithalamus
a. Pineal gland
b. Habenula
c. Thin roof over third ventricle
The Telencephalon (Cerebrum) (pp.484-489)
- Cerebral white matter
a. Projection tracts
- Internal capsule
- Corona radiata
b. Commissural tracts
- Anterior commissure
- Posterior commissure
- Corpus callosum
c. Association tracts
- Long association fibers
- Short association fibers
- Gross anatomy of cerebral cortex
a. Thickness and area
b. Gyri, sulci, fissures
- Central sulcus
- Parieto-occipital sulcus
- Lateral sulcus
c. Lobes
- Frontal lobe
- Parietal lobe
- Occipital lobe
- Temporal lobe
- Insula
- Histology of cerebral cortex
a. Stellate cells
b. Pyramidal cells
c. Stratification of neocortex
- Basal nuclei (corpus striatum)
a. Caudate nucleus
b. Lentiform nucleus
c. Amygdala
d. Claustrum
e. Role in motor control
- Limbic system
a. Location
b. Functions
- Learning and memory
- Motivation
- Emotional and sexual response
- Personality
- Basic drives
Functions of the Neocortex (pp.489-498)
- Brain waves and the electroencephalogram
- Sleep
a. Function of sleep
b. Hypothalamic control centers
c. Sleep stages 1 - 4
d. Paradoxical (REM) sleep
- Motor control
a. Premotor area
b. Precentral gyrus (primary motor area)
- Somatotopy and motor homunculus
- Decussation of motor fibers
- Somatic sensation
a. Postcentral gyrus (primary sensory area)
b. Decussation
c. Somatotopy and sensory homunculus
- Special senses
a. Visual cortex
b. Auditory cortex
c. Olfactory cortex
d. Gustatory cortex
- Association areas
a. Somatosensory association area
b. Visual association area
c. Auditory association area
d. Frontal association area
- Cerebral lateralization
- Language
a. Wernicke's area
b. Angular gyrus
c. Broca's area
d. Affective language area
e. Lesions and language defects
- Memory
a. Short-term memory (STM)
b. Long-term memory (LTM)
c. Cellular aspects of LTM


