1. The lymphatic system collects excess tissue fluid and returns itto the bloodstream at the _______________ veins.

2. Pathogens in the lymph are often detected as it filters throughorgans called the _______________.

3. Which lymphatic organs are best positioned to detect inhaled andingested pathogens?

4. Neutrophils undergo a reaction called the _______________ to producestrong oxidizing agents that kill nearby bacteria.

5. Redness, heat, and pain are some of the classic signs of adefensive reaction called _______________.

6. Basophils secrete an anticoagulant called _______________ and avasodilator called ___.

7. Cells infected with viruses may secrete chemical messages called _______________, whichactivate natural killer cells and macrophages and interfere with viral invasion of healthycells.

8. HIV attacks a class of lymphocytes called _______________, and thusknocks out their central coordinating role in humoral and cellular immunity.

9. An antibody molecule consists of two long _______________ and two short _______________ of polypeptides.

10. Helper T cells respond only to antigen fragments that aredisplayed by various _______________ cells.

11. Prior to the endocytosis of an antigen by a B cell, the antigenmust _______________ multiple receptor sites on its surface.

12. DNA rearrangements called _______________ enable B cells toproduce far more different antibodies than the total number of genes in the genome.

13. _______________ is a process in which antibody molecules cause clumping offoreign cells or antigen molecules.

14. The only class of T lymphocytes that directly attack foreigncells is the _______________ cells.

15. _______________ is asevere circulatory failure that results when an antigen is introduced into the bloodstreamof a hypersensitive person.

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