Hematology Case Histories - Case 8

A 36-year-old male complained of fatigue, anorexia, weight loss, dyspnea on exertion, and a sense of abdominal fullness. An examination of peripheral blood and bone marrow resulted in the following:

Complete blood count (CBC):
Erythrocytes 2.8 million/cu mm
Leukocytes 180,000/cu mm
Thrombocytes (platelets) 53,000/cu mm
Hematocrit 26%

Differential:
Lymphocytes = 85% of all leukocytes

Bone marrow examination demonstrated a tremendous predominance of small lymphocytes (>90%). The bone marrow was so tightly packed that it aspirated with difficulty. The spleen was moderately enlarged, and there was generalized lymph node enlargement.

1. What is the primary disorder of this person?

2. Define leukocytosis.

3. What is the cause of the leukocytosis?

4. Define thrombocytopenia.

5. What is the cause of the thrombocytopenia?

6. Define anemia.

7 What is the cause of the anemia?

8. What is the cause of the feeling of abdominal fullness?

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