1. The two translocations cause the same phenotype because they disrupt the same gene

on chromosome 11.

2. Both leukemia and homeotic mutations disrupt developmental pathways.

3. If the chromosome 11 gene implicated in leukemia is an oncogene, it is mutated or

overexpressed. If it is a tumor suppressor, it is deleted or inactivated.

4. A mutation that causes acute leukemia occurs in somatic cells, not germline cells, so it

is not inherited.

5. The mutation in an intron can offset the reading frame or disrupt intron/exon splicing.

6. Repeated sequences on two different chromosomes might cause non-homologs to pair

during meiosis or mitosis, causing a translocation.

7. A gene sequence found in widely unrelated species is probably ancient, inherited from

a common ancestor.