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Molecular Biology 2nd Edition Robert F. Weaver | ||||||
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Chapter 7
- The E. coli catabolite gene activator protein (CAP) is thought to activate lac operon transcription by direct contact with RNA polymerase. Chen et al. show by protein-protein photocrosslinking that CAP directly contacts the carboxyl-terminal domain (CTD) of the -subunit of RNA polymerase. (Chen, Y., Y.W. Ebright, and R.H. Ebright. 1994. Identification of the target of a transcription activator protein by protein- protein photocrosslinking. Science 265:90-92)
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