Chapter 50
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50.1 A skeletal system supports movement in animals.


 There are three types of skeleton: hydrostatic skeletons, exoskeletons, and endoskeletons.
 Bone is formed by the secretion of an organic matrix by osteoblasts; this organic matrix becomes calcified.

1. What are the two major components of the extracellular matrix in bone? What structural properties does each component have? How do the two components combine to make bone resistant to fracture?

Bone Structure
Bone Function

Running Improperly
Osteoporosis

 
50.2 Skeletal muscles contract to produce movements at joints.


 Freely movable joints surround the articulating bones with a synovial capsule filled with a lubricating fluid.
 Skeletal muscles can work together as synergists, or oppose each other as antagonists.

2. What are the three types of joints in a vertebrate skeleton? Give an example of where each type is found in the body.
3. What is the difference between a skeletal muscle's origin and its insertion?

Skeletal Muscles

Skeleton
Muscles

Sports & Fitness

Movable Joints

 
50.3 Muscle contraction powers animal locomotion.


 A muscle fiber contains numerous myofibrils that are composed of myofilaments of myosin and actin.
 There are small cross-bridges of myosin that extend out toward the actin; the cross-bridges are activated by the hydrolysis of ATP so that it can bind to actin and undergo a power stroke that causes the sliding of the myofilaments.
 When Ca++ binds to troponin, the tropomyosin shifts position in the thin filament, allowing the cross-bridges to bind to actin and undergo a power stroke.
 The release of Ca++ from the sarcoplasmic reticulum is stimulated by impulses in the muscle fiber produced by neural stimulation.
 Slow-twitch fibers are adapted for aerobic respiration and are resistant to fatigue; fast-twitch fibers can provide power quickly but produce lactic acid and fatigue quickly.
 Cardiac muscle cells have gap junctions that permit the spread of electric impulses from one cell to the next.
 Cardiac and smooth muscles are involuntary; the contractions are automatically produced in cardiac muscle and some smooth muscles.
 Animals have adapted modes of locomotion to three different environments: water, land, and air.

4. Of what proteins are thick and thin filaments composed?
5. Describe the steps involved in the cross-bridge cycle. What functions does ATP perform in the cycle?
6. Describe the steps involved in excitation-contraction coupling. What functions do acetylcholine and Ca++ perform in this process?
7. How does a somatic motor neuron stimulate a muscle fiber to contract?
8. What is the difference between a muscle twitch and tetanus?
9. Why can't a myocardium produce a sustained contraction?
10. How does smooth muscle differ from skeletal muscle in terms of thick and thin filament organization, the role of Ca++ in contraction, and the effect of stretching on the muscle's ability to contract?
11. What do all modes of locomotion have in common?

Striated Muscle Contraction
Actin-myosin Crossbridges
Muscle Contraction Action Potential
Walking

Muscle Cell Function
Activity: Muscle Contraction
Muscle Twitch Physiology
Smooth and Cardiac Muscle

Climbing the Walls

Muscle Stimulation Pattern
Thick and Thin Filaments
Muscle Contraction

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