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Chapter 19: Human Genetics |
1. Relevance of Topic
This chapter lends itself easily to discussions that are relevant to most persons. A variety of diseases and syndromes can be used to introduce the chapter material and signify the importance of studies in this area.
2. Continuity
The previous chapter on genetic engineering is critical in discussions of treating human genetic disease, as well as in discussions involving the moral issues surrounding human genetic engineering experiments.
3. Demonstration Activities
Text section 19.1
1. Figure 19.1 shows three typical pedigrees.
Text section 19.2
1. Show a picture illustrating a normal distribution of human heights, a classic example of polygeny.
2. Show Figure 19.3, which quantitatively examines the height example.
Text section 19.3
1. Figure 19.4 illustrates the ABO blood type system.
2. Figure 19.5 shows the ABO compatibility chart for transfusion.
Text section 19.4
1. Figure 19.7 summarizes the Rh factor phenomenon.
2. Show Figure 19.8 to illustrate how fetal cells and maternal cells can be mixed.
Text section 19.5
1. Show Figure 19.9, a drawing of chromosomes showing banding patterns.
2. Show a photograph of chromosomes that have been stained and show these patterns.
Text section 19.6
1. Figure 19.10 is a basic illustration of nondisjunction.
2. Figure 19.1 is a karyotype and photograph illustrating Down syndrome.
Text section 19.7
1. Photographs of persons who have various sex chromosome abnormalities can be shown, including Figures 19.13 and 19.14.
2. Show a picture of a calico cat (Figure 19.15) when discussing mosaics.
3. Figure 19.17 shows Barr bodies.
Text section 19.8
1. Figure 19.19 illustrates hybridization and its use in mapping the TK gene to chromosome 17.
Text section 19.9
1. Figure 19.20 illustrates linkage disequilibrium.
2. RFLPs are illustrated in Figure 19.21.
3. Pictures of crime scenes can be shown when discussing the use of these techniques in forensics.
Text section 19.10
1. Figure 19.22 shows a map of human chromosome 7 and locations of markers.
Text section 19.11
1. Figure 19.24 illustrates the transformation of the CFTR gene.
2. Pictures or new stories related to gene therapy are usually easily found and could be shown during discussions of this topic.
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