Probably your most formidable tasks with this chapter will be deciding first how much chemistry your students already have and second how much chemistry they need to fulfill the objectives of your course. This chapter is packed with material and many of your students are already afraid of the word chemistry; many of them will be overwhelmed -- particularly the non-science majors.
I suggest you begin your preparation by reading the summary at the end of the chapter. Keep the summary points in mind as you skim through the rest of your course. What are your specific course objectives? Decide what is necessary for your particular class, go back through the text to see how those points are presented, and then teach chemistry accordingly.
This chapter is quite "readable." Lewis does a good job with the presentation; some of my own students did "student reviews" of this chapter for the author and their comments were generally quite favorable. Your students will not have too much difficult with the quality of the material; it is only the quantity that I caution you about, particularly if you have students who have had no exposure to chemistry before.
For your particular class, it may be appropriate to include some of the material in this chapter with other chapters. For instance, you might wish to defer the material on nucleic acids until you reach Chapter 14, Chromosomes. Decide what is best for your students.
You might wish to copy and distribute to your students the Overview of Chapter Objectives flowchart found at the beginning of this Instructor's Manual Chapter.
Be positive about chemistry. Don't tell your class that chemistry is hard. They've already heard this from everyone else! Interestingly, for many people, once they catch on to the basics of chemistry, they find it amazingly easy and wonder why it took so long to "get it." But before they "got it", they were certain chemistry was absolutely impossible.
I urge you to make liberal use of drawings and props in teaching this chapter.
Use the Mastering Concepts questions within the chapter.
Use ball-and-stick models. If your school does not have molecular models, make some models from marshmallows or fruits and toothpicks. Many of these students need that visual, spatial sense.
I definitely suggest a quiz (or a non-quiz) at the beginning of the next class period after you start your chemistry discussion. Correct the quiz in class (even if you don't collect the points) because it is important to clear up any misconceptions immediately. And there will be some!
Start by using the formula p + n = aw (protons plus neutrons equals atomic weight). Then put a C (for carbon) on the board. Ask how many protons this C has. Under the C put "6 p" and then ask for the atomic weight of carbon. Leave some room beneath your "6 p", draw a line and write 12 beneath the line. Refer back to the formula and ask how many neutrons this atom of carbon has. Between the "6 p" and the line fill in "6 n." State that this is one isotope of carbon, specifically Carbon 12, and put a "12" next to the C.
To the right of the C-12, write another C. Ask how many protons this atom has. Again write "6 p" and draw a line. Tell them that the weight of this particular atom is 13 and write "13" beneath the line. Ask how many neutrons this particular atom has. Fill in the "7 n" and add the 13 next to the C. Explain that this is Carbon 13.
Follow this pattern for Carbon 10, and Carbon 14. Explain that all of these are isotopes of carbon.
Proteins can be classified in many ways but according to function the simplest way to classify them is as structural or regulatory.
The order of the shells is the primary structure. The way the shells are spatially in relation to one another is the secondary structure. (I show how I can physically move these R groups so they are not always the same.) Then I gently let the necklace fall on my hand and state that the way it lays over itself is its tertiary structure. I further explain that because of such attractions as hydrogen bonds and sulfide bonds, this structure will remain constant under a given set of conditions. To demonstrate the quaternary structure, I explain that quaternary implies two or more necklaces so if I had two I would hold them up together and let them fall together on my hand. The way the two strands interacted would be my quaternary structure.
That necklace analogy may sound a bit simplistic. But, I have had more than one student come back more than a year later and say that recalling the necklace made the concept perfectly clear when working with proteins in more advanced courses.
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