Chapter 17 Outline

Regulation of Gene Activity

Operons, levels of control of gene expression in eukaryotic cells, and cancer as a failure in genetic control are topics covered in this chapter.

Chapter Outline

In this chapter outline, the learning objectives and the selected key terms are given for each major head in the chapter.

Prokaryotes Utilize Operons (p. 260)

1. List and define the components of an operon. Explain why the lac operon

is an inducible operon and the trp operon is a repressible operon.

Selected Key Terms: operon, promoter, operator, repressor, inducer, inducible

operon, represssible operon, corepressor, regulator gene

2. List the levels of control of gene expression in eukaryotic cells.

Eukaryotes Utilize Various Methods (p. 262)

3. Provide evidence that genes are regulated at all levels of control in eukaryotes.

4. Using Barr bodies as an example, explain how heterochromatin is genetically

inactive.

5. Using lampbrush chromosomes and giant (polytene) chromosome puffs as

examples, explain how euchromatin is genetically active.

heterochromatin, euchromatin, Barr body, transcription factor

Cancer Is a Failure in Genetic Control (p. 268)

6. Describe cancer as a failure in genetic control.

7. Discuss the discovery of oncogenes and tumor-suppresser genes and their possible

functions.

8. List some recommendations to prevent the development of cancer.

cancer, tumor, metastasis, carcinogen, oncogene, tumor-suppressor gene,

proto-oncogene
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