Chapter 1 Extended Lecture Outline




Chapter Outline

THE SCIENCE OF BIOLOGY

		Darwin's Voyage to South America on HMS Beagle	fig 1.1

		Example of the Exploration of Biology

BIOLOGY IS THE SCIENCE OF LIFE

		Biologists Study Life in Many Different Ways

		Brief Consideration of the Characteristics of Living Things
			Composed of one or more ordered cells	fig 1.2
				Hierarchical organization
				Cells   tissues   organs   systems   organism
				Organism   population   ecosystem   biome   biosphere
			Display sensitivity and respond to stimuli	fig 1.3a
			Capable of growth, development and reproduction	fig 1.3b
			Have regulatory mechanisms to coordinate functions	fig 1.3c

WHY IS BIOLOGY IMPORTANT TO YOU?

		Biology Is Interesting Because of Its Great Variety

		Biology Affects the Quality of Our Future
			Study population and disease
			Manage earth's resources

		Opportunities for Biologists
			Researchers
			Genetic engineers
			Physicians
			Biology teachers

THE NATURE OF SCIENCE

		Deductive Reasoning
			Analysis of specific cases using general principles
			Used extensively in math and philosophy
			Example: Eratosthenes' estimation of earth's circumference	fig 1.4

		Inductive Reasoning
			General principles derived from observations, experiments
			Used extensively in and is definition of science
			Example: Newton and gravity

		Testing Hypotheses	fig 1.5
			Hypothesis: suggested explanation for facts
			Subject to future rejection or alteration
			Tested with observations and experiments
				Reject those inconsistent with data
				Conditionally accept those consistent with data

		Controls
			Variables are factors that influence processes 
			Two experiments carried out in parallel
				In one all variables except one being tested are kept constant
				In control experiment test variable not changed
			Differences in parallel experiments attributed to test variable

		The Importance of Prediction
			Most useful hypothesis makes predictions
			Prediction that is rejected may cause rejection of hypothesis
			Example: Einstein's hypothesis of relativity
				Provisionally accepted due to lack of invalidating experiment
				Light bent in eclipse corroborated prediction, supported hypothesis

		Theories
			Hypotheses that are often tested, never rejected
			Supported by a great deal of evidence
			Acceptance most certain, but provisional

		The Scientific Method
			Experimental testing of hypothesis 
			Based upon systematic, objective collection of data
			Hypothesis constructed with creative insight
			Types of scientific research
				Basic research extends boundaries if scientific knowledge
				Applied research directed toward scientific industry
			Scientific work must be communicated via papers in scientific journals

HISTORY OF A BIOLOGICAL THEORY: DARWIN'S THEORY OF EVOLUTION

		Evolution Provides an Example of the Scientific Process

		Historical Background
			Charles Darwin 	fig 1.6
				Author of On the Origin of Species
				Published in 1859 after 30 years of observation 
			Traditional beliefs
				All organisms resulted from direct actions of a Creator
				Species unchangeable over course of time
			Darwin's alternative
				Does not support or refute existence of a Creator
				Natural laws change and improve Creator's work via evolution

		Details of Voyage (1831 to 1836) 
			Stops along coasts and islands of southern hemisphere	fig 1.7
			Observations in Patagonia and Galapagos Islands	fig 1.8

		Return to England After Voyage
			Publication of study of life and geology during voyage
			Forty years of formulation of the evolutionary process

DARWIN'S EVIDENCE

		Due to Supporting Evidence Acceptance of Evolution Inevitable
			Darwin's rejection of supernatural explanations
			New evidence supporting geological events
				True age of earth greater than a few thousand years
				Fossil evidence of many unfamiliar species
				Lyell's writings on species extinction and emergence

		What Darwin Saw	tbl 1.1
			Extinct species related to living organisms	fig 1.8
			Characteristics of species varied from place to place
				Appearance of tortoises dependent on location	fig 1.9
				Slight changes in appearance after island isolation
			Great variety of organisms on young volcanic islands
				Resembled forms on mainland, not distant places	fig 1.10
				Supports evolution, refutes independent creation 

		Darwin and Malthus
			Malthus wrote  Essay on the Principles of Population
				Populations of organisms increase geometrically	fig 1.11
				Food supply increases arithmetically
				Unchecked population could reproduce to fill the world
				Nature acts to check population growth via death
			Darwin concluded evolution dependent on natural selection

		Natural Selection
			Organisms produce more offspring than will survive
			Surviving organisms are superior in certain attributes	fig 1.12
				Pass these characters to offspring
				Changes nature of population as a whole
			Similar in intent to artificial selection
				Selection for traits practiced by breeders
				Animals breed true for traits concentrated in them
				Example: domestic pigeons

PUBLICATION OF DARWIN'S THEORY

		First Draft Completed in 1842, Years of Refinement

		Letter from Wallace with Same Ideas Stimulated Completion and Presentation

		Some Views Not Accepted, Including Man Evolving From Apes

EVOLUTION AFTER DARWIN: TESTING THE THEORY

		Collection of Evidence by Darwin and Contemporaries

 		The Fossil Record
			Darwin predicted links between groups of organisms	fig 1.13
			Microscopic fossils 3.5 billion years old
			Graded series of vertebrate fossils

		The Age of the Earth, 4.5 Billion Years, Determined by Radioactive Decay

		The Mechanisms of Heredity
			Genes unknown at Darwin's time
			Laws of inheritance explain genetic variation

		Comparative Anatomy
			Comparison of vertebrate forelimb bones	fig 1.14
			Homologous structures: same origin, different structure and function
			Analogous structures: similar structure and function, different origin

		Molecular Biology
			Sequence of DNA provides genetic information
			Construct family trees and estimate rates of evolution
				Measure degree of change in DNA code
				Compare to known fossil evidence	fig 1.15

		Development
			Similarities in developmental stages of species	fig 1.16
			"Ontogeny recapitulates phylogeny"

HOW THIS TEXT IS ORGANIZED TO HELP YOU LEARN BIOLOGY

		Natural Selection and Evolution Are the Essence of Biology

		Logical Arrangement of Text
			Basic principles in first half of text
				Cell biology: molecular, subcellular, cellular levels
				Genetics: organismal level
				Evolution: population level
				Ecology: community, global levels
			Examination of organisms in second half of text
				Microorganisms
				Plants
				Animals
				Function of vertebrate body
			Chapter information is cumulative

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