Chapter 2 Extended Lecture Outline




Chapter Outline

INTRODUCTION

Organisms Are Chemical Machines
			Composed of molecules
			Content reshuffled via chemical reactions
			Water is most important molecule of life

	Beginning of Universe 
			20 billion years ago
			Residual energy still detectable
			Organisms composed of molecules that are composed of atoms

ATOMS:  THE STUFF OF LIFE

		Universe Composed of Matter
			All matter made of atoms	fig 2.1
			Very small size, resembling solar system
			Composed of smaller subatomic particles	fig 2.2
				Protons (+) and neutrons (0) in central nucleus
				Electrons (-) in circular orbits around nucleus
					Same number as protons to balance charge
					Dictates chemical activity
			Atomic number = number of protons
				Neutrons and protons have same mass
				Only protons have electrical charge
			Mass versus weight
				Mass is the amount of a substance
				Weight is the force of gravity exerted on it
				Atomic mass = mass of protons + mass of neutrons
			Mass measured in daltons
				Proton or neutron is roughly 1 dalton
				Electron is 1/1840 dalton, practically mass-less
			Subatomic particles seen indirectly via collisions

		Isotopes
			All atoms of an element have the same atomic number (proton number)
			An element cannot be broken into other substances by chemical means
			Isotopes of an element have:
				Same number of protons, different number of neutrons
				Same number of electrons, thus same chemical properties
			Example: carbon-12 versus carbon-13 and carbon-14	fig 2.3
			Unstable forms, like carbon-14, decay
				Emit radioactive energy
				Half-life = time for half of a sample's atoms to decay
				Potential harmful side effects, exposure must be  limited

		Electrons
			Electrically neutral atom has same number of electrons and protons
			Electron orbit maintained by electrical attraction
			In ions the number of electrons and protons are different
				Element that possesses a net electrical charge 
				Positive charge if electron lost, a cation
				Negative charge if electron gained, an anion

		Electrons Determine the Chemical Behavior of Atoms
			Arrangement determines chemical properties of element
			Orbital describes probable, not actual location
			Shapes differ	fig 2.4
				Inner s orbitals are spherical
				More distant p orbitals are dumbbell-shaped
				Maximum number of two electrons per orbital
			Orbitals extremely far away from nucleus, atom mostly empty space
			Nuclei of different atoms rarely contact one another
			Electrons interact, determine chemical behavior

		Energy Within the Atom
			(-) electrons are attracted to (+) protons
			Energy required to keep electrons in orbit
			Electron energy of position is potential energy	fig 2.5
				Moving electron away from nucleus 
					Requires energy 
					Electron then has more potential energy
				Moving electron toward nucleus
					Releases energy
					Electron then has less potential energy
			Exchange of electrons between molecules	fig 2.6
				Oxidation is a loss of electrons
				Reduction is a gain of electrons
				Chemical energy stored in electrons by oxidation-reduction reactions
			Energy level schematics
				Electrons represented as concentric rings called energy levels	fig 2.7
				Electrons in outer most rings hold more energy
				Don't confuse energy levels and electron orbitals

		The Periodic Table	fig 2.8
			Eight groups of repeating chemical properties
			Based on interactions of valence electrons in outer shell
			Maximum of eight electrons in outer shell of elements important to life
				Elements at maximum are inert, not reactive
				Elements with one less than maximum are highly reactive
			Octet rule (rule of eight) states that atoms want their outer shell full

CHEMICAL BONDS HOLD MOLECULES TOGETHER

		Molecule Is a Stable Group of Atoms
			Compounds are molecules containing more than one kind of element
			A chemical bond is the holding force

		Ionic Bonds Form Crystals	fig 2.9
			Atoms attracted by opposite electrical charges
			Atoms donate or receive electrons from other atoms
			Example: sodium chloride, common table salt
				Sodium atom, loses electron = Na+
				Chlorine atom, accepts electron = Cl-
			Resulting atoms become charged ions, an ionic compound
			Bond forms by attraction of ions of opposite charges
				Not between two individual atoms
				Between one ion and all oppositely charged ions in vicinity

		Covalent Bonds Build Stable Molecules
			Two atoms share one or more pairs of valence electrons
			Example: single bonded diatomic hydrogen (H2)	fig 2.10
				Hydrogen has unpaired electron and unfilled outer level
				Two atoms combine, each nucleus shares two electrons
			Bond requires close proximity of atoms to one another
			Covalent bonds are very strong
			Double bond shares two pairs of electrons, stronger than a single bond
			Structural formulas:  H - H or O = O
			Molecular formulas:  H2 or O2

		Chemical reactions Make and Break Chemical Bonds
			Involve shifting atoms without change in number or identity
				Reactants:  original, pre-reaction molecules
				Products: molecules resulting from a reaction
			Influenced by several factors
				Temperature:  heat increases rate
				Concentration:  reactant versus product have opposite effect
				Catalyst:  special substance increases rate

		Molecules with Several Covalent Bonds
			Atoms can share electrons with more than one other atom
			Example: carbon, has six electrons, four in the outer level
				To satisfy octet rule must gain four electrons
				Thus can form four chemical bonds

THE ATOMS OF LIFE

		Distribution of Elements in Living Organisms	tbl 2.1
			Only eleven elements found in greater than trace amounts
			Elements are generally light, atomic mass less than 21

		Most Abundant Elements:  N, O, C, H
			All form covalently bonded molecules
			Possess breakable chemical bonds to make a variety of molecules
			Reflect predominance of water (H2O) in organisms
			Many form gaseous molecules that are soluble in water

WATER :  THE CRADLE OF LIFE

		Unique Properties of Water Necessary for Living Organisms	fig 2.11
			Exists as liquid at temperature of earth's surface
			Provides a medium in which other molecules can interact
			Composes two-thirds of most organisms
			Forms weak chemical associations 
			Simple atomic structure, H2O	fig 2.12

		Water Acts Like a Magnet
			Electronegativity attracts electrons of water molecules
			Has distinct ends, each with a partial charge
				Polar molecule results from magnet like poles
				Polarity is crux of chemistry of water and life
			Charge separation results in polar nature
				Most stable configuration is tetrahedron, bond angle 104.5%
					Partial (d+) charges at apexes opposite hydrogens
					Partial (d-) charge at oxygen
				Polar molecules interact with one another 
					Opposite charges attract, form hydrogen bonds	fig 2.13
					Bonds are transient, cumulative effects important
					Hydrogen bonds affect physical properties of water	tbl 2.2

		Water Clings to Polar Molecules
			Cohesion is attraction of water to water
				Results in surface tension of water	fig 2.14
				Causes things to get wet in water
			Adhesion is attraction of water to another molecule
				Attraction is electrostatic
				Results in capillary action, water rises in thin tube	fig 2.15
				Height inversely proportional to tube diameter

		Water Stores Heat
			Exhibits high specific heat
				Amount of heat to change temperature of a substance
				Associated with and proportional to polarity
				Thermal energy must first disrupt hydrogen bonds
					Heats up slowly 
					Retains heat longer than surroundings
			Forms ice with decrease in temperature	fig 2.16
				Crystal-like lattice of hydrogen bonds
				Less dense than liquid water
			High heat of vaporization
				Amount of heat required to change water to vapor
				Evaporation of water produces cooling effect

		Water Is a Powerful Solvent
			Water molecules gather around charged molecules
			Example: table sugar (sucrose)
				Water forms hydrogen bonds with OH- groups of sucrose
				Each sugar molecule surrounded by cloud of water molecules
				Cloud is called the hydration shell
			Hydration shells form around ions	fig 2.17

		Water Organizes Nonpolar Molecules
			Water excludes nonpolar molecules 
			Preferentially forms hydrogen bonds with itself
			Minimizes disruption of hydrogen bonding
				Hydrophobic:   not soluble in water, nonpolar
				Hydrophilic:   soluble in water, polar
			Hydrophobic exclusion
				Forces nonpolar molecules to associate together
				Shapes molecules with nonpolar regions

		Water Ionizes
			Ionization is spontaneous formation of ions
				Results from breaking of covalent bonds of water
				Proton (H+) dissociates from molecule
				Remainder of molecule is OH-
			Mole of a substance is its molecular mass
				Corresponds to combined atomic mass of all molecules
				Molar concentration of H+ ions in water is 10-7 mole/liter
			pH scale quantifies H+ concentration	fig 2.18
				pH = negative log of H+ ion concentration = -log[H+]
				Acid = low pH value, <7, high concentration of H+
				Base = high pH value, >7, low concentration of H+
				Scale is logarithmic, change of one on scale is really tenfold
			Changes in environmental pH caused by acid precipitation	fig 2.19
				Serious impact on living organisms
				Erodes even limestone and marble	fig 2.20

		Buffers
			pH of body fluids is about 7
			Minimize changes in H+ and OH- concentration
			Act as reservoirs for H+
				Donate to solutions when concentration falls
				Take from solutions when concentration increases
			Example: carbonic acid/bicarbonate in blood	fig 2.21


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