
Table of Contents
Preface
Acknowledgements
Key Terms
Chapter Objectives
Drug Problems in America
Drugs and Medicines
Drugs Use and People Problems
Basic Definitions
Drug
Medicine
Drug Misuse
Drug Abuse
Psychoactive Drug
Drug Classifications
Drug Problems: Health-Related Consequences
Delay in Seeking Proper Medical Treatment
Reduction in Personal Problem-Solving Effectiveness
Experience of Additional Health Problems
Use of Adulterated Drugs
Suicide
HIV Infection and AIDS
The Drug Scene: An Overview
The Drug-Crime Relationship
The Drug Scene: Prospects for the Future
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Chapter 2 - The Allure of Drugs
Key Terms
Chapter Objectives
Why People Use and Abuse Drugs
Altered Consciousness
Social Definition of Drug Abuse
A Drug for Every Ailment
Rebellion Against the Establishment Versus Recreational Use
Using and Abusing Drugs: A Behavioral Analysis
Predisposing Factors in the Use and Abuse of Drugs
Enabling Factors in the use and Abuse of Drugs
Reinforcing Factors in the use and Abuse of Drugs
The Family's Influence on Drug Abuse
Theories on Drug Abuse and Drug Dependence
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Chapter 3 - Pharmacology
Key Terms
Chapter Objectives
Pharmacology
How Drugs Enter the Body
Drug Distribution and Elimination
The Blood-Brain Barrier
Metabolism and Excretion
Drug Actions
Factors Influencing Drug Actions
Dose-Response Relationship
Age
Body Weight
Gender
Time
Disease
Mind-Set
Environmental Setting
The Nervous System
Organization of the Nervous System
The Nerve Cell
Neurotransmitters
Drugs and Synaptic Transmission
The Brain
Medulla Oblongata
Pons
Midbrain
Diencephalon
Thalamus
Hypothalamus
Limbic System
Cerebellum
Cerebrum
Drug Dependence
The Continuum of Drug Use and Drug Dependence (Addition)
Criteria for Psychoactive Drug Dependence
Psychological Dependence
Tolerance
Physical Dependence
Withdrawal Syndrome
The Placebo Effect
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Part Two - The Depressents
Chapter 4 - Alcohol
Key Terms
Chapter Objectives
Alcohol in Society
Historical and Cultural Aspects
From Temperance to Prohibition to Repeal
Attitudes Toward Drinking
Ambivalence and the Drinking Society
Drinking Today
Drinking Among College Students
Personal and Social Uses of Alcohol
Social Drinking
Ritualistic Drinking
Dietary Drinking
Drinking for Altered Consciousness
Alcoholic Beverages
Wine
Beer
Distilled Spirits
Equivalent Servings
Alcohol Within the Body
Absorption
Distribution
Oxidation
Intoxication
Mechanism of Impairment
Alcohol and States of Consciousness
Psychological Aspects of Intoxication
Short-Term Effects of Alcohol
Long-Term Effects of Alcohol
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Chapter 5 - Alcohol Abuse and Alcoholism
Key Terms
Chapter Objectives
Problem Drinking
Problem Drinking and Alcohol Abuse
Alcohol Abuse and Work Performance
Drinking and Job Behaviors
Work-Related Factors and Alcohol Abuse
Alcohol-Related Law Violations and Violence
Public Intoxication
Driving Under the Influence
Alcohol-Related Crimes of Violence
Alcohol-Related Accidents
Falls
Drownings
Fires
Alcohol-Impaired Driving and Auto Crashes
Prenatal Alcohol Abuse
Fetal Alcohol Syndrome
Principal Features of FAS
Fetal Alcohol Effects or Alcohol-Related Birth Defects
Mechanism of Impairment
Prevention of FAS and FAE
The Family and Problem Drinking
Children of Alcoholics
Co-Dependence
Alcoholism
Overview
Possible Causes of Alcoholism
Signs and Symptoms of Alcoholism
Treatment and Rehabilitation
The Intervention Process
Reduction and Problem Drinking
Parents Who Drink and Their Children
Host and Hostess Responsibilities
For those Who Drink
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Chapter 6 - Narcotics
Key Terms
Chapter Objectives
General Characteristics of Narcotics
Classification of Opiods
Medical Use and Addiction
Other Opioid Effects
Narcotics of Natural Origin
Opium
Morphine
Codeine
Thebaine
Semisynthetic Narcotics
Hydromorphone
Oxycodone
Etorphine
Heroin
Synthetic Narcotics
Meperidine
Propoxyphene
Fentanyl
Endogenous Opioids
Historical and Legal Perspectives
Treatment of Narcotic-Dependent Individuals
Detoxification
Maintenance Therapy
Narcotic Antagonists
Therapeutic Communities
Psychotherapeutic Communities
Psychotherapeutic Approaches
Narcotics Anonymous
Acupuncture
A Multimodality Approach to Treatment
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Chapter 7 - Sedative-Hypnotics and Inhalants
Key Terms
Chapter Objectives
Introduction
Drugs that Calm and Promote Sleep
Motivational Factors in Misuse and Abuse
General Characters
Historical Perspectives
Barbiturates
Barbiturate Overdose
Barbiturate Dependence
Barbiturate Withdrawal
Nonbarbiturate Sedative-Hypnotics
Chloral Hydrate
Glutethimide
Methaqualone
Other Nonbarbiturate hypnotics
Self-Care for Inducing Sleep
Minor Tranquilizers
Meprobamate
Benzodiazepines
Rohypnol
Other Antianxiety Medications
Inhalants
Reasons for Use
General Effects
Categories of Abuse Inhalants
Health Hazards
Prevention of Inhalant Abuse
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Part Three - The Stimulants
Chapter 8 - Tobacco
Key Terms
Chapter Objectives
Introduction
Tobacco: America's Smoke-Drug
Source of Pleasure and Disease
Personal Decisions with Social Consequences
Patterns and Trends of Tobacco Use
Profile of Tobacco Users
The Changing Cigarette
The Evolutions of Tobacco Regulation
The Nonsmokers' Liberation Movement
Specific Efforts at Restriction
Psychological Aspects of Smoking
A New Product for Personal Needs
A Learned Behavior
Psychological Rewards
Factors in Smoking Behavior
Health Consequences of Smoking
Constituents of Tobacco Smoke
Nicotine Addiction
Research Findings
Passive Smoking
Smoking and Cardiovascular Disease
Smoking and Lung Cancer
Laboratory Experiments
Autopsy Studies
Chronic Obstructive Lung Disease
Pulmonary Emphysema
Chronic Bronchitis
Smokeless Tobacco
Typical Users
Origins of Modern Use
Cancer and Smokeless Tobacco
Noncancerous and Precancerous Oral Effects and Smokeless Tobacco Use
Nicotine Exposure and Smokeless Tobacco
Rewards Versus Risks
Reducing the Risks
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Chapter 9 - Cocaine and other "Chemical Uppers"
Key Terms
Chapter Objectives
Introduction
Chemical Uppers
Basic Perspectives
Common Effects
Various Use Patterns
Drug Dependence and Compulsive Behavior
Cocaine
Unique Characteristics
Medical Uses
Historical and Legal Aspects
Patterns of Using Cocaine
Oral Use
Snorting
Intravenous Injection
Combined Use with Depressants
Freebasing
Crack Smoking
Effects of Cocaine
Mechanism of Action
Major Influencing Factors
Some Undesirable Effects
Cocaine Babies
Life-Threatening Consequences
Amphetamines
Effects of Amphetamines
Amphetamine Dependence
Historical and Legal Aspects
Medical Uses and Amphetamines
Caffeine
Historical Aspects
Effects of Caffeine
Caffeinism
Caffeine Dependence and Tolerance
Caffeine, Pregnancy, and Birth Defects
Caffeine and Diseases
Reducing Caffeine Intake
Methcathinone
Effects of Methcathinone
Manufacture and Control of Cat
Ephedrine
Other Plant Stimulants
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Part Four - The Mind-Expanding Euphoriants
Chapter 10 - Psychedelics and Phencyclidine
Key Terms
Chapter Objectives
Introduction
The Psychedelic State; Mind Expansion
Major Characteristics
Psychological Hazards
Types of Psychedelic Experiences
The Range of Response
Pharmacological Effects
Historical Aspects
Early Use of Mushrooms
Religious Use of Peyote
Laboratory Synthesis
Nonmedical Use
Illegal and Popular
Lysergic Acid Diethylamide
The LSD Trip
LSD Hazards
The Other Psychedelics
Peyote and mescaline
Psylocybine
DMT
Morning Glory Seeds
Nutmeg
MDA
MDMA
DOM(STP)
Chemical Variations
Phencyclidine
Effects of PCP
PCP Overdose
Historical Aspects
Legal Prohibition
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Chapter 11 - Marijuana
Key Terms
Chapter Objectives
Introduction
Marijuana: A Brief Description
Historical and Legal Aspects of Marijuana
The Marijuana Tax Act
Decriminalization and Legalization of Marijuana
Antiparaphernalia Laws
The Current Scene
Potency is Up
Effects More Clearly Understood
Age of First Use
Domestic Production
Marijuana and THC
Cannabinoids
Tetrahydrocannnabinol
THC Content
Paraquat
Metabolism of THC
Urine Testing for THC
The Marijuana High
Behavioral and Psychosocial Effects
The Role of Neurotransmitters
Acute Effects
Automobile Accidents
Anxiety/Panic Reaction
Tolerance and Dependence
Passive Marijuana Smoking
Chronic Effects: Areas of Concern
Amotivational Syndrome
Flashback
Mental Illness
Ther Respiratory System
The Cardiovascular System
Reproduction and Sexual Function
The Immune System
In Conclusion
Medical Uses of Marijuana
Synthetic THC
Legalization of Medical Marijuana
Therapeutic Value
Glaucoma
Chemotherapy - Causes Nausea and Vomiting
Additional Medical Uses
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Part Five - Medicines
Chapter 12 - Over-the-Counter Drugs
Key Terms
Chapter Objectives
Introduction
Our Fascination with Drugs
Benefits and Risks
Drug Misuse
Over-the-Counter Versus Prescribed Drugs
Classification of OTC Drugs
Analgesics
Salicylates
Versatility of Aspirin
Side Effects of Aspirin
Nonsalicylates
Weight-Control Products
Cold Remedies
Sleep Aids
Stimulants
Herbal Remedies
Self-Medication
Guidelines for Self-Medication
Safety and Effectiveness of OTC Drugs
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Chapter 13 - Prescription Drugs
Key Terms
Chapter Objectives
Introduction
Prescribed Drugs: Potent Chemotherapeutic Agents
The Benefit-Risk Equation
Prescriptions and Drug Labels
Reading a Prescription
Labels on Prescribed Medicines
Using Prescribed Drugs Wisely
Frequently Used Prescription Drugs
Prescription Drug Classes
Oral Contraceptives
Combination OCs
Estrogen Hormone Agents
Progestin Hormone Agents
Side Effects of Oral Contraceptives
Noncontraceptive Benefits
The Future of Drug-Based Contraception
Emergency "Morning After" Oral Contraception
Chemically Induced Abortion
Other New Drugs of Interest
Side-Effects and Adverse Reactions of Prescribed Drugs
Secondary Side Effects of Medicines
Therapeutic Index
Preventive measures
Polypharmacy: Drug-Drug Interactions
Food-Drug Interactions
Drug Information for Patients
Generic Drugs
Drug Names
Chemical Equivalence versus Bioavailability
Generic Drug Prescription
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Chapter 14 - Alcohol and other Drugs in Special Populations
Key Terms
Chapter Objectives
Introduction
Alcohol and Drug Use and Abuse Among Women
Closing the Gender Gap
Gender-Related Hazards
Sexual Dysfunction
Connecting Substance Abuse with Sex and Violence
Psychoactive Drugs and Pregnancy
Female Athletes and Drugs
Racial and Ethnic Minorities
African Americans
Hispanic Americans
Native Americans and Alaskan Natives
Asians and Pacific Islanders
Drug Use and Abuse Among Athletes
Ergogenic Drugs
Anabolic-Androgenic Steroids
Dangerous Alternatives to Anabolic-Androgenic Steroids
Creatine
Recreational Drugs
Alcohol and Drug Use and Abuse Among the Elderly
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Chapter 15 - Drug-Abuse Prevention
Key Terms
Chapter Objectives
Introduction
Prevention: The War on Drugs
General Strategies of Preventing Drug Abuse
Supply Reduction Strategy
Demand Reduction Strategy
Inoculation Strategy
The Macroapproach
Intervention Levels of Abuse Prevention
Primary Prevention Level
Secondary Prevention Level
Early Detection and Referral
The Intervention Process
Tertiary Prevention level
Substance Abuse in the Workplace
Drug Testing in the Workplace
Employee Assistance Programs
Drug Law Enforcement
Routine Enforcement Techniques
Federal Law Enforcement Agencies
Federal Control Mechanisms
State Legal Control mechanisms
The Antiparaphernalia Movement
Drug Laws of Other Nations
Alternative Behaviors as Alcohol and Other Drug Abuse Prevention
Responsible Uses as Alcohol and Other Drug Abuse Prevention
Situational Responsibilities
Health Responsibilities
Safety Responsibilities
The Role of the Family
Drug Abuse: A Family Affair
Identification of Drug Use and Abuse
Guidelines for Parental Intervention
Understanding the Stages of Adolescent Chemical Use
The Family and Primary Prevention
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Chapter 16 - Alcohol, Tobacco, and Other Drug Prevention Education
Key Terms
Chapter Objectives
Introduction
Basic Considerations: The What and Why of Alcohol; Tobacco; and Other Drug Prevention Education
Goals of ATOD Education in the Schools
Healthy People 2000 Objectives
Planning and Strategies: The How of Alcohol, Tobacco, and Other Drug Education
Educational Planning
Curricular Strategies
Some Concluding Thoughts
Resources for ATOD Education
Key Elements of Effective Durricula
Prepackaged ATOD Curricula
School Policies on Alcohol and Other Drugs
Elements of a comprehensive Policy
Student Assistance Programs
Chapter Summary
World Wide Web Sites
Review Questions and Activities
References
Appendix A: A Resource Guide for ATOD
Information
Glossary
Index
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