Dr. Mermel has worked in academia and the medical foods industry. She was the lead researcher and author of numerous scientific investigations and publications exploring gender-linked differences in body fat production in subjects fed high carbohydrate diets. She also published research exploring dietary methods of reducing muscle tissue loss during periods of reduced food consumption.

Since 1990 Dr. Mermel has had her own consulting practice. Her clients include school district-, university-, and hospital-based wellness programs; small food manufactures; pharmaceutical food manufactures; private patients; and publishing companies. Dr. Mermel also co-authored Focus on Nutrition, ©1995, an introductory nutrition text for college students.

Dr. Mermel is currently Clinic Director for PROMED Wellness and Weight Management Systems at the Pacific Arthritis Center in Santa Maria, California, and was recently appointed Senior Health Risk Management Advisor to the Nutrition Division of Novartis Life Science Corporation.