In conclusion, we have demonstrated that SLs, particularly glyco-SLs, are involved in theformation or stabilization of axonal branches in cultured hippocampal neurons. We are currentlyexamining the levels and types of SLs synthesized during development, and their targeting to axonalor dendritic domains, in order to distinguish between the various possible molecular mechanisms thatcould account for these effects. --Andreas Schwarz et al., Journal of Chemical Biology
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