Functional Group Questions
 

Qu : The structure of EPOTHILONE A, a compound with anticancer activity similar to Taxol is shown to the right. (a) Identify the functional groups in Epothilone A. (b) What is the hybridization at each of the following atoms in Epothilone A ?   C1 C8 C12 C14 C17 C19 (c) Arrange the following bonds in Epothilone A in order of decreasing length:     C14-C15       C15-C17         C17-C18 (d) What type of bonding MOLECULAR orbitals are involved in the bonds between  C3-C4 and  C17-C18 ?

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  Isomers Questions

Qu 1 : Draw the constitutional isomers of C₆H₁₄.

Qu 2 : Draw the constitutional isomers of C₅H₁₀.

Qu 3 : Draw the constitutional isomers of C₃H₆O.
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Thermodynamics Questions
 

Qu 4 :

Gasoline mainly consists of two isomers of octane:  I = 2,2-dimethylhexane, DHc = -1304.6 kcal/mol and,  II =  2,2,3,3-tetramethylbutane, DHc = -1303.0 kcal/mol.  Knowing that the heats of combustion, DHc C (graphite) = -94.05 kcal/mol and DHc H2 (gas) = -57.8 kcal/mol, calculate the heat of formation, DHf for each of  the isomers of octane. Based on this data, which isomer is the most stable ?  Is this consistent with what you would have predicted ?

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