Summary of Carboxylic Reactions

Chapter 20: Carboxylic Acid Derivatives. Nucleophilic Acyl Substitution

Reactions for Interconverting Carboxylic Acids Derivatives

Here is a table that summarizes the methods for interconverting carboxylic acid derivatives. The more important reactions in emphasized in bold, and the reactions of the parent carboxylic acids (chapter 19) in blue.

To make -> From
	-	RCO₂^-	R'OH	H₂O	R₂NH	H₂O, HO^-
	-	-	R'OH	H₂O	R₂NH	H₂O, HO^-
	-	-	R'OH, heat H+ or B-	H₂O, H₃O⁺ heat	R₂NH	H₂O, HO^- heat
	SOCl₂ or PCl₃	Heat, -H₂O	R'OH, heat H+	-	R₂NH heat	HO^-
	-	-	-	H₂O, H₃O⁺ heat	-	H₂O, HO^- heat
	-	RCOCl	R'-Br or -I	H₃O⁺	-	-