Chapter 20: Carboxylic Acid Derivatives. Nucleophilic Acyl Substitution

Interconversion Reactions of Acid Anhydrides

	esters
	acids
	amides

Reaction type:  Nucleophilic Acyl Substitution

Summary

• Acid anhydrides are the second most reactive of the carboxylic acid derivatives and can therefore, be fairly readily converted into the other less reactive carboxylic acid derivatives (see above).
• A base in often added to neutralise the carboxylic acid by product that is formed.