Chapter 22: Amines
Reduction of Azides
Reaction type : Oxidation - Reduction
Summary
Azides,
R-N
3
, can be reduced to primary amines,
R-NH
2
Reagents : either lithium aluminum hydride (LiAlH
4
) / ether solvent or catalytic hydrogenation (
e.g.
H
2
/Pd)
Alkyl azides are prepared by
nucleophilic substitution
(
SN2
) by azide ion, N
3
-
, of
primary or secondary alkyl halides
.
Related reactions
Reduction of Nitriles
Reduction of Nitro compounds
Reduction of Amides
