Chapter 23: Aryl Halides

Aryl Grignards Summary

• Aryl Grignards are formed by the reaction of aryl halides (X= Cl, Br or I) with magnesium metal.
• Typical solvents are normally anhydrous diethyl ether or tetrahydrofuran.
• Halide reactivity : I > Br > Cl
• Aryl Grignards undergo the sample types of reactions as alkyl Grignard reagents (review)
• Organolithium reagents can also be made.
• Aryl Grignard reactions allow for the introduction of C substituents other than via Friedel-Crafts alkylation or acylation reactions.

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